Designed to eliminate the complexities of microscopy without compromising performance, the EVOS™ line of cell imaging systems makes cell imaging accessible to almost every lab and budget. Find out which EVOS Cell Imaging System is right for you.

The EVOS lineup

Fluorescence systems

Fluorescence imaging has never been easier.


Simple fluorescence imaging with increased flexibility.


Perfect for live cell imaging, image stitching, and area scanning.

Transmitted light systems
EVOS® XL Core Cell Imaging System

All-in-one transmitted-light system, perfect for cell culture.

EVOS® XL Cell Imaging System

Transmitted-light system with advanced capabilities.


Compare all EVOS models and find out for yourself.

EVOS Cell Imaging System accessories

EVOS Light Cubes

For EVOS FL and FL Auto

EVOS Objectives

For all EVOS systems (except FLoid stations)

EVOS Vessel Holders

For all EVOS systems (except FLoid stations)

Which Cell Imaging System Is Right for You?

Basic transmitted light digital inverted system Advanced transmitted light digital inverted system Basic fluorescence system Advanced fluorescence systemFully automated fluorescence system
xl core
Perfect for cell culture & routine cell maintenance
Perfect for more advanced colormetric assays
Perfect for quick fluorescence visualization
Perfect for multichannel fluorescence imaging & transfections
Perfect for a variety of advanced automated applications
High-resolution LCD display 12.1" 15" 15" 15"22" touch screen
Available objectives 1.25x–100x 1.25x–100x 20x fixed 1.25x–100x1.25x–100x
Fluorescent channels 0 0 3 fixed 4 (changeable)*4 (changeable)*
Camera Color CMOS Color CMOS Monochrome CCD Choice of color or monochrome CCDDual monochrome (CCD) and color (CMOS)
Transmitted light (bright-field & phase-contrast)
Epifluorescence imaging
Cell counting Automated
Time-lapse imaging
Image tiling/stitching
Automated well/area scanning
Thermo Fisher Cloud Save files to Cloud through computer
Weight 9.1 kg (20.1 lb)15.3 kg (33.7 lb)11.8 kg (26.0 lb)15.3 kg (33.7 lb)20 kg (44.1 lb)
Dimensions H: 553mm (21.0") W: 318mm (12.5") D: 406mm (16.0") H: 578mm (22.8") W: 355mm (14.0") D: 470mm (18.5") H: 578mm (22.8") W: 355mm (14.0") D: 470mm (18.5") H: 578mm (22.8") W: 355mm (14.0") D: 470mm (18.5") H: 322mm (12.7") W: 343mm (13.5") D: 472mm (18.6")
Flow cytometry grant program
Viability and cell counting, reusable slide

An EVOS system is a must-have in your lab for cell imaging—whether you’re capturing images for publication, teaching, or research. From cell culture to complex protein analysis to multichannel fluorescence imaging, EVOS cell imaging systems help you perform a variety of routine and specialty applications. Our proprietary LED light cube technology minimizes photobleaching, offers >50,000 hours of LED illumination, and permits precise intensity adjustments—with no darkroom and no consumables costs.

Generate publication-quality images

In today’s competitive scientific environment, generating publication-quality images is critical to your success. To help ensure that you get the publication-quality images you need, EVOS systems give you top-of-the-line imaging components, including:

  • High-quality cameras and optics to capture high-resolution images
  • LED illumination to produce superior signal-to-noise ratios
  • Easy-to-use image capture and processing software for ready-to-publish images

Check out a list of publications citing the use of EVOS systems

The power of LED illumination

  All EVOS fluorescence cell imaging systems utilize LED light sources. That means you get high-intensity output over a short light path for the most efficient fluorophore excitation.
  • Shorter light path enables better detection of fluorescent signals
  • Continuous illumination gives consistent results
  • >50,000-hour bulb lifetime lowers your laboratory costs
  • Adjustable light intensity reduces photobleaching

Revolutionary light path

By placing the LED light cube as close as possible to the objective turret, the number of optical elements in the light path is minimized. High-intensity illumination over a short light path increases the efficiency of fluorophore excitation, providing better detection of weak fluorescent signals.

Constant illumination, consistent results


Mercury arc lamps can decrease in intensity by 50% in the first 100 hours of operation—plus, images acquired in different sessions cannot be quantitatively compared using mercury illumination without complicated calibrations. Because EVOS systems have continuous light cube intensity, users can rely on consistent illumination and can compare results quantitatively from images acquired on different days.

Figure 1. Stability comparison.

Lower long-term maintenance costs using LED bulbs


The LED bulbs on the EVOS systems are rated for >50,000 hours (~17 years), compared to 300 hours for a typical mercury bulb (and 1,500 hours for a metal halide bulb). That means a 70–75% savings in the overall upkeep of your instrument.

Figure 2. Illumination costs over time.

Higher transmission efficiencies with hard-coated filters

Hard-coated filter sets are more expensive, but they have sharper edges and significantly higher transmission efficiencies that typically result in >25% more light transmission compared to traditional soft-coated filters. With the EVOS system’s hard-coated filter sets, your light cubes cost less over time. Plus, you will have brighter fluorescence, higher transmission efficiencies, the ability to detect faint fluorescence signals, and better signal-to-noise ratios.

Figure 3. Superior transmission efficiencies are observed using hard-coated filters on the EVOS instruments compared to soft-coated filters. Excitation filter (purple), emission filter (red), dichroic mirror (green); Alexa Fluor488 excitation (blue), Alexa Fluor 488 emission (pink).