Generating transgenic plants is key to the introduction of new crop traits and carrying out gene studies, both in discovery and applied settings. The development of genetically modified plants often requires a complex design of DNA elements to achieve optimum expression. Based on Xanthomonas effector proteins, GeneArt® Precision TALs are custom DNA-binding proteins that allow you to accurately target any locus in the genome. TAL technology has been shown to be effective in a broad range of organisms, including plants, algae, and fungi. The first of their kind, GeneArt® Precision TALs are ideal for plant research scientists, offering research-use access with a clear licensing path for commercial use through the Two Blades Foundation.
Every plant genome locus is within your reach
Precision TALs derived from Xanthomonas, a genus of plant pathogens. The pathogen specifically recognizes DNA of the host with a protein containing 17–18 repeats of approximately 34 amino acids each. The nucleotide specificity is conferred by amino acids 12 and 13 within each repeat. Each nucleotide in the target DNA is recognized by one repeat, and this 1-to-1 relationship can be used to specifically target any locus in the genome.
- Learn more about GeneArt® Precision TALs
GeneArt® Precison TALs fit your project and budget
Recent improvements in GeneArt® Precison TAL design and manufacturing have allowed us to significantly increase the flexibility and reduce the cost of genome editing with designer GeneArt® Precision TALs. Our new pricing should allow all researchers to experience the power of GeneArt® Precison TALs for all-around freedom and unlimited genome targeting.
- Industrial: $3,000/pair
- Academic: $2,000/pair
Ordering GeneArt® Precision TALs for Plants
The fastest and easiest way to design, edit, optimize, and order GeneArt® Precision TALs is through the GeneArt® portal.
The ordering process is simple; just follow these three steps:
- Select the functionality (effector domain) of your TAL from Table 1. For details, refer to the ‘TALEN functionality overview’
- Select the product name from Table 1.
- Then place your order through our online design tool within the GeneArt® portal, or you can download (.xls) and complete the TALEN order form and email it to firstname.lastname@example.org.
Table 1. Available effector domains
For Research Use Only. Not for use in diagnostic procedures.