Plasmid Isolation
Successfully isolate quality plasmid DNA. Choose from our wide range of high-performing, cost-effective plasmid purification technologies designed to help you overcome common plasmid prep issues, such as low recovery and the presence of impurities.

Prep sizes and purity grades are available to suit every application.

Which plasmid DNA isolation technology is right for you?

Gold standard for ultrapure, high quality Rapid isolation of molecular biology quality Efficient and automatable high-throughput isolation
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  PureLink® HiPure Plasmid Kits GeneJET Plasmid DNA Purification Kits MagJET Plasmid DNA Purification Kits
Purity grade Molecular, Transfection Molecular Molecular
Prep size Mini - Giga Mini - Maxi Mini
Total protocol time 30-120 min 15 - 60 min 40 min
Yield < 20 µg – 14 mg 20 µg – 1000 µg < 20 µg
Throughput Medium MediumHigh
Technology Anion exchange Silica membraneMagnetic beads
Prep size Miniprep Midiprep Maxiprep Megaprep Gigaprep 
Overnight bacterial culture volume 1-5 mL 25-100 mL 100-500 mL 500 mL-2.5 L 2.5-5 L
Approximate Yield

Up to 40 µg

Up to 200 µg

750- 800 µg

Up to 4 mg

Up to 12 mg

Plasmid DNA purity grades

Plasmid purification is available in molecular, transfection, and advanced-transfection grade. Molecular-grade plasmid isolation technologies are generally faster, more cost-effective and are best suited for basic molecular biology applications. Transfection-grade may be used for applications that demand greater purity and higher yields. And advanced-transfection grade may be used for all applications from transformation to transfection of sensitive cells, such as primary and suspension cells.

Learn more about plasmid DNA purity grades

Downstream application Purity grade
  Molecular Transfection Advanced-transfection
  GeneJET kits PureLink HiPure kits PureLink Endotoxin-Free kits
Sensitive transfection (i.e. primary cells)    

Vaccine research



Gene therapy research    

In vitro transcription

Standard transfection  
Nucleic acid labeling

NEW   Nucleic Acid Purification and Analysis Support Center
Find tips, troubleshooting help, and resources for your nucleic acid purification & analysis applications.

DNA Purification Brochure
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