A thermal cycler (also called thermocycler) is an instrument that employs precise temperature control and rapid temperature changes to conduct the polymerase chain reaction (PCR). PCR is used to create billions of copies of a DNA sequence for use in a wide array of downstream procedures including cloning, sequencing, expression analysis, and genotyping. Our engineers have been designing and manufacturing high-quality Applied Biosystems™ thermal cyclers since 1987; these instruments are renowned for their reliability, accuracy, and user-friendly interfaces.

Which thermal cycler is right for you?

Economical option for everyday cycling Elegant design, smart choice For robust thermal cycling and diagnostic applications Most flexible and highest throughput

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2720 Thermal Cycler

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SimpliAmp™ Thermal Cycler

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Veriti™ Thermal Cycler**

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ProFlex™ PCR System

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Block formats
  • 96-well 0.2 mL
  • 96-well 0.2 mL
  • 96-well 0.2 mL
  • Fast 96-well 0.1 mL
  • 384-well 0.02 mL
  • 60-well 0.5 mL
  • 3 x 32-well 0.2 mL independently controlled
  • 96-well 0.2 mL VeriFlex™
  • 2 x 96-well 0.2 mL
  • 2 x flat block for digital applications
  • 2 x 384-well 0.02 mL
Temperature optimization None
  • 3-zone VeriFlex™ Blocks on 96-well systems
  • 6-zone VeriFlex™ Blocks on 96-well systems
  • 6-zone VeriFlex™ Block on 96-well system
  • 2-zone VeriFlex™ Block on 32-well system
User inferface Keypad 8.4 in. touch screen 6.5 in. touch screen 8.4 in. touch screen
Up to 96 reactions Up to 96 reactions Up to 384 reactions Up to 480,000 reactions
Max block ramp rate*** 2.7°C/sec 4.0°C/sec 5.0°C/sec 6.0°C/sec

**Also available as an FDA Class 1/ CE-IVD labeled device, click here for details
***For information about how ramp rates are calculated, click here


Service options


NEW PCR and cDNA Synthesis Support Center
Find tips, troubleshooting help, and resources for your end-point PCR and cDNA applications.