Automated Thermal Cycler (ATC)

Complete solution for automated PCR

Looking to automate your PCR workflow? The Applied Biosystems Automated Thermal Cycler (ATC) offers the flexibility, reliability, and performance needed in a complete PCR automation system.

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Designed for easy integration with a robotic platform

  • Flexible modular design saves space on deck
  • Easy-to-install software solutions for robotic integration: SiLA Rapid Integration™ standard*–compatible software and prewritten application programming interfaces (APIs)
  • Free software for stand-alone operation allows assay optimization before integration


Automated instrument features

  • Automated lid for hands-free operation with a liquid handler or plate stacker
  • Heated cover slides forward to cover the plate nest, enabling thermal contact and minimizing evaporation
  • Automated plate ejectors help ensure consistent plate positioning for half-skirted or fully-skirted 96-well plates

Software solutions

Fully integrate your automated system with our easy-to-install software:

  • Integration-compatible SiLA rapid integration coding language for maximum flexibility when integrating on your robotic platform
  • Direct software allows you to run your Automated Thermal Cycler before installing your robot. This allows you to optimize your assays even before robotic integration, if desired.

Compatible robotics

We are currently working with robotics/liquid handling system manufacturers on the development of drivers compatible with the Applied Biosystems Automated Thermal Cycler (ATC).

Manufacturer Model Contact information
Thermo Fisher Scientific
  • Thermo Scientific Orbitor
  • Thermo Scientific Spinnaker
  • Thermo Scientific F7
  • Thermo Scientific Momentum
Hamilton Robotics
  • VANTAGE Liquid Handling System
  • Microlab STAR
  • Microlab NIMBUS
Beckman Coulter Inc.
  • Biomek i7 Automated Workstation
  • Biomek i5 Automated Workstation
  • Biomek FXP Automated Workstation
  • Biomek NXP Automated Workstation
  • Biomek 4000 Automated Workstation
Hudson Robotics Inc.
  • SOLO™ Pipettor
  • PlateCrane EX™ robot arm
  • PlateCrane SciClops™ robot arm
  • If your robot is listed here, contact us or the robot manufacturer for driver and integration information.
  • If you don't see your system listed here, we can work with you and your robot manufacturer on integration options.

Please contact Technical Support for any questions regarding driver development and robotic integration.

Space-saving design with small thermal cycler footprint

  • Flexible modular design helps save space on a robotic deck
  • Separate control panel module and block module can be stacked or separated to fit available deck or bench space
  • Choice of 10 cm, 1 m, and 3 m cables accommodates variable locations for the control module under the thermal cycler, under the deck, or up to 3 m away from the unit

Use the ATC as a stand-alone PCR thermal cycler

Flexible software can easily be connected to your robot’s software interface or be used to control the ATC as a stand-alone instrument. Test your instrument using the ATC desktop application before integrating it into your robotic automation system (Figures 1 and 2).

Figure 1. Easy-to-use desktop software application included with the stand-alone version of the ATC.

Figure 2. Easy visualization and monitoring of temperature and ramp rate data during your PCR run.


The Applied Biosystems MicroAmp EnduraPlate Optical Plates with Barcode have been exclusively designed for use with the Automated Thermal Cycler to provide reliable, consistent PCR results.

Automated Thermal Cycler — Customer Stories

Ordering information


Applied Biosystems Thermal Cycler, Plastics and Services Brochure

PCR and cDNA Synthesis Support Center 
Tips and troubleshooting help

School of Molecular Biology, PCR Education
Technical content for new and experienced molecular biologists

Thermal Cycler Software and Firmware Files
Download the latest updates for your instrument

Interested in private label thermal cyclers?
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We provide award-winning service options for all Applied Biosystems thermal cyclers.

Service plans

  • Rapid Exchange minimizes interruptions from unplanned instrument downtime
  • Global Repair Center provides a cost-efficient way to maximize uptime and achieve superior performance

Additional services available

Instrument qualification service: Have one of our engineers perform temperature qualifications at your site. You may also contact Instrument Services to purchase a temperature verification tool and perform the qualification yourself.