targeted sequencing


Single day, single tube, hundreds of genes targeted sequencing
exome sequencing


Unravel disease-causing variants in your research exome sequencing
transcriptome sequencing

Transcriptome sequencing

Flexible, simple, affordable RNA-Seq within reach transcriptome sequencing
genome sequencing


From outbreak research to discovery genome sequencing

The Ion S5™ and Ion S5™ XL systems provide the simplest DNA to data workflow for targeted sequencing with industry-leading speed and affordability. So you can spend less time doing biology and more time answering the critical questions in your research.  From small gene panels to exomes or transcriptomes, the Ion S5 and Ion S5 XL systems let you leverage a single benchtop instrument that scales to your research and throughput needs.

Combined with Ion AmpliSeq™ technology for target selection, the Ion Chef™ System for automated library and template preparation, and Ion Reporter™ Software for automated variant annotation, targeted sequencing on the Ion S5 and Ion S5 XL systems is simpler than ever with less than 45 minutes hands-on time.

Read the Ion S5 System application notes ›

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Find tips, troubleshooting help, and resources for your next-gen sequencing applications.