Whether for basic research, drug discovery, or future therapeutic applications, stem cell differentiation requires standardized culture methods to ensure reproducible and reliable results. Gibco media, supplements, and substrates provide you with an easy-to-use, flexible set of tools for targeted differentiation to your desired cell lineage. Our differentiation portfolio simplifies your workflow and provides you with more control – allowing for faster, more efficient systems.

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Featured stem cell differentiation products

PSCs to NSC with no EB formation.

PSC Neural Induction Medium

PSC DE Induction Kit

TH-positive mid-brain dopaminergic neurons from PSCs.

Dopaminergic Neuron Differentiation Kit

3 simple steps. 1 simple kit.

PSC Cardiomyocyte Differentiation Kit

PSC DE Induction Kit

Two media. 48 hours.

PSC Definitive Endoderm Induction Kit


Ectoderm is the outer layer of the early embryo and gives rise most notably to neural cells and skin.


Mesoderm is the middle layer of the developing embryo and gives rise to muscle, kidney, and blood.


Endoderm is the innermost primary germ layer and gives rise to multiple systems including gut, liver, lung, pancreas, and thyroid.


Technical resources