Biotin Blocking

Mammalian cells and tissues contain biotin-dependent carboxylases, which are required for a variety of metabolic functions. These biotin-containing enzymes often produce substantial background signals when biotin–streptavidin or biotin–avidin detection systems are used to identify cellular targets. Endogenous biotin is particularly prevalent in mitochondria and in kidney, liver, and brain tissues.




SKU Name Size
E21390 Endogenous Biotin-Blocking Kit 1 kit