Antibodies that detect CD4 can be used in several scientific applications, including Flow Cytometry, Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) and Immunocytochemistry. These antibodies target CD4 in Human, Mouse, Rat, Canine and Chicken samples. Our CD4 monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse, Rat, Rabbit and Goat. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to CD4. Find the CD4 antibody that fits your needs. Choose from 1 of 412 CD4 antibodies, which have been validated in experiments with 7848 publications and 120 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you re looking for, contact us today to develop custom antibodies for specific targets, species and applications. View more
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
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