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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome, which is characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. [provided by RefSeq, May 2016].
a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 17; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif 17; ADAM metallopeptidase with thrombospondin type 1 motif, 17; ADAMs; ADAM-TS 17; ADAMTS17; ADAM-TS17; ADAMTS-17; ATS17; AU023434; disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17; FLJ16363; FLJ32769; metalloendopeptidases
100 µL
100 µL
100 µL
100 µg
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