GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013].
(N-acetylneuraminyl)-galactosylglucosylceramide; Beta-1,4 N-acetylgalactosaminyltransferase 1; beta-1,4-N-acetyl-galactosaminyl transferase 1; beta-4N-acetylgalactosaminyltransferase; beta1,4GalNAC-T; GALGT; GalNAc-T; GD2 synthase, GM2 synthase; GM2/GD2 synthase; SIAT2; UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T); UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase