Serine hydrolase that catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir and valganciclovir. Activates valacyclovir to acyclovir. May play a role in detoxification processes. It is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol.
31--; Biphenyl hydrolase-like protein; Biphenyl hydrolase-related protein; Bph-rp; BPHL; Breast epithelial mucin-associated antigen; MCNAA; Poly(ADP-ribose) glycohydrolase; VACVase; Valacyclovir hydrolase; Valacyclovirase