The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia. [provided by RefSeq, May 2010].
bromo domain-containing protein disrupted in leukemia; Bromodomain and WD repeat-containing protein 3; BRWD3-H; BRWD3-I; BRWD3-K; BRWD3-P; novel WD repeat domain protein