Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
2CD2 antigen; CD2; CD7; CD7 antigen (p41); Erythrocyte receptor; GP40; LFA-2; LFA-3 receptor; p41 protein; Rosette receptor; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen CD2; T-cell surface antigen Leu-9; T-cell surface antigen T11/Leu-5; TP41