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CD4/CD62L Antibodies

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. View more

Synonyms

CD4; CD4 antigen (p55); CD4 antigen p55; CD4 receptor; CD62 antigen-like family member L; CD62L; gp90-MEL; hLHRc; L-selectin; LAM-1; LECAM1; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lselectin; Lyam-1; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; sL selectin; soluble L selectin; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; TQ1

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