The protein encoded by this gene belongs to the CDC2-like protein kinase family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5, a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
CDC-like kinase 4; DKFZp686A20267; Dual specificity protein kinase CLK4; protein serine threonine kinase Clk4