May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
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5830484J08Rik; cell cycle control protein SDP35; DEP domain-containing protein 1A; DEP.8; DEPDC1-V2; DEPDC1A; SDP35