Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
DHFRL1; DHFRP4; Dihydrofolate reductase 2, mitochondrial; dihydrofolate reductase like 1; dihydrofolate reductase pseudogene 4; Dihydrofolate reductase, mitochondrial; dihydrofolate reductase-like 1; Dihydrofolate reductase-like protein 1; mitochondrial