This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6.
(rat homolog) mouse id-associated protein 1; DnaJ (Hsp40) homolog, subfamily C, member 2; DnaJ homolog subfamily C member 2; DnaJ homolog subfamily C member 2, N-terminally processed; Gliosarcoma-related antigen MIDA1; Id associate 1; M-phase phosphoprotein 11; MIDA1; Mouse Id associate 1; MPHOSPH11; MPP11; ZRF1; ZUO1; zuotin related factor 1; zuotin related factor 2; Zuotin-related factor 1