Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron- bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).
1700030A21Rik; CSL-type zinc finger-containing protein 3; Diphthamide biosynthesis protein 4; DnaJ (Hsp40) homolog, subfamily C, member 24; DnaJ homolog subfamily C member 24; DNAJC24; DPH4; DPH4 homolog (JJJ3, S. cerevisiae); DPH4, JJJ3 homolog; ZCSL3; zinc finger, CSL domain containing 3; zinc finger, CSL-type containing 3