DP family contains at least two members, DP-1 and -2. Structurally, DP-1 and -2 are relatively conserved, yet their expression appears to be tissue specific. E2F-1, a functional target for the tumor suppressor protein Rb, heterodimers with DP-1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.
cell cycle regulatory transcription factor DP1; down-regulated in liver cancer stem cells; DRTF1; DRTF1-polypeptide 1; E2F dimerization partner 1; E2F-related transcription factor; OTTHUMP00000018767; Transcription factor Dp-1