Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a subunit of dolichyl-phosphate mannosyltransferase and acts as a stabilizer subunit of the dolichyl-phosphate mannosyltransferase complex.
Dolichol-phosphate mannose synthase subunit 3; Dolichol-phosphate mannosyltransferase subunit 3; Dolichyl-phosphate beta-D-mannosyltransferase subunit 3; dolichyl-phosphate mannosyltransferase polypeptide 3; DPM synthase complex subunit 3; DPM synthase subunit 3; Mannose-P-dolichol synthase subunit 3; MGC125904; MGC125905; MGC34275; MPD synthase subunit 3; prostin 1; Prostin-1; testicular tissue protein Li 58