The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; D1beta dopamine receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor 5; dopamine receptor D1B; DRD 1B; DRD 5; Hd5dr; MGC10601
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