This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.
Endo G-like 1; ENDOGL1; ENDOGL2; Endonuclease G-like 1; endonuclease G-like 2; ENGL; ENGL-a; ENGL-b; Nuclease EXOG, mitochondrial