Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Endogenous retrovirus group K member 7 Env polyprotein; ERVK-7; HERV-K(III) envelope protein; HERV-K102 envelope protein; HERV-K_1q22 provirus ancestral Env polyprotein