Her-3, also known as c-erbB-3, is a Type 1 membrane protein found in numerous cell types. It is a member of the EGF receptor protein family, and is activated by neuregulins and NTAK. Her-3 levels have been found to be elevated in certain human tumor cell lines suggesting that it may play a role in some malignancies. Her-3 is a receptor for heregulin and is capable of mediating HGL-stimulated tyrosine phosphorylation of itself.
avian erythroblastosis oncogene B 3 receptor; c-erbB-3; C-errB-3; ERBB3; Glial growth factor receptor; human epidermal growth factor receptor 3; MDA BF 1; p180 ErbB3; p45 sErbB3; p85 sErbB3; Proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine protein kinase ERB3; Receptor tyrosine-protein kinase erbB-3; tyrosine kinase type cell surface receptor HER3; Tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
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