Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
down regulated by Ctnnb1, a; Down-regulated by CTNNB1 protein A; family with sequence similarity 126, member A; Hyccin; Protein FAM126A
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