Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.
bA421P11.4; family with sequence similarity 48, member A; p38-interacting protein; p38IP; protein FAM48A; suppressor of Ty 20 homolog; transcription factor (p38 interacting protein); Transcription factor SPT20 homolog; tumor rejection antigen
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