FGF1 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
Acidic fibroblast growth factor; AFGF; Beta-endothelial cell growth factor; ECGF; ECGF-beta; ECGFA; ECGFB; Endothelial cell growth factor; endothelial cell growth factor, alpha; endothelial cell growth factor, beta; FGF-1; FGF-alpha; FGF1; FGFA; Fibroblast growth factor 1; fibroblast growth factor 1 (acidic); HBGF-1; HBGF1; Heparin-binding growth factor 1; Heparin-binding growth factor 1 [Precursor]
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