BAPTA ((1,2-bis(2-Aminophenoxy)ethane-N,N,N',N'- tetraacetic acid) is a highly selective calcium chelator. BAPTA has spawned many of the most familiar fluorescent indicators for calcium and other ions. BAPTA and its analogs including BAPTA-AM have proven most critical in cell physiology research where they have been essential in defining the mechanisms underlying inter- or intracellular calcium homeostasis and calcium dependent exocytosis. BAPTA and its analogs may also find application in the study of diseases in which the regulation of excitatory neurotransmitter release and uptake has been disturbed.
Calcium-chelate transporter; CCT; feline leukemia virus subgroup C cellular receptor family, member 2; Feline leukemia virus subgroup C receptor-related protein 2
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