Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
H2b 613; H2B histone family, member Q; H2B/q; histone 2, H2be; histone cluster 2, H2be; Histone H2B type 2-E; Histone H2B-GL105; Histone H2B.q