IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Cytokine ZCYTO20; IFN-lambda-2; IFN-lambda-3; IFN-lambda2; IFNL2; IFNL3; IL-28A; IL-28B; IL28B; IL28C; interferon alpha; Interferon lambda-2; Interferon lambda-3; interferon-lambda2; interleukin 28; interleukin 28A; interleukin 28B; Interleukin-28A; Interleukin-28B; ZCYTO20; ZCYTO22