Interferon-activable protein 202 belongs to the HIN-200 family and contains two HIN-200 domains. It is reported to inhibit transcriptional activity of several transcription factors, including NF-kappaB p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. It has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. It is an interferon-inducible protein which is responsible for Lupus susceptibility and is induced by Interleukin-6.
Ifbip-1; Ifi-202; Ifi202; Ifi202a; interferon activated gene 202A; Interferon-activable protein 202; Interferon-activatable protein 202a (Ifi-202a) (Interferon-inducible protein p202a); Interferon-inducible protein p202; Lupus susceptibility protein p202; p202