Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms.
eag-related protein 3; ERG-3; Ether-a-go-go-related gene potassium channel 3; ether-a-go-go-related protein 3; KCNH7; potassium channel erg3; potassium channel protein erg3; potassium channel subunit HERG-3; potassium channel, voltage gated eag related subfamily H, member 7; Potassium voltage-gated channel subfamily H member 7; potassium voltage-gated channel, subfamily H (eag-related), member 7; Voltage-gated potassium channel subunit Kv11.3