This gene encodes a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2.
Basic transcription element-binding protein 5; BTE-binding protein 5; BTEB5; Krueppel-like factor 14; Kruppel-like factor 14; Transcription factor BTEB5