The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Four transcript variants encoding three different isoforms have been found for this gene.
Colony stimulating factor 1 (macrophage); CSF-1; Lanimostim; macrophage colony stimulating factor 1; Macrophage colony-stimulating factor 1; MCSF; MGC31930; osteopetrosis
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