MAGEC1 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This protein contains a large number of unique short repetitive sequences in front of the MAGE-homologous sequence, thus is about 800 residues longer than the other MAGE proteins. This gene is expressed in a significant proportion of tumors of various histological types, whereas it is silent in normal tissues, except testis. The function of this gene is unknown.
Cancer/testis antigen 7.1; cancer/testis antigen family 7, member 1; CT7.1; MAGE-C1 antigen; melanoma antigen family C, 1; melanoma antigen family C1; Melanoma-associated antigen C1