MBDT1 is a putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. MBDT1 specifically binds to monomethylated and dimethylated 'Lys-20' on histone H4.
MBT domain-containing protein 1
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