This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants.
DBL's big sister; FLJ12122; Guanine nucleotide exchange factor DBS; mcf.2 transforming sequence-like; MCF2 transforming sequence-like protein; MCF2-transforming sequence-like protein; OST oncogene; RP11-98F14.2
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