This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. A pseudogene for this locus is located on chromosome 6.
DKFZp686L18234; mesoderm specific transcript; mesoderm specific transcript homolog; mesoderm specific transcript homolog (mouse); Mesoderm-specific transcript homolog protein; Mesoderm-specific transcript protein; MEST; MGC111102; MGC8703; paternally expressed gene 1; Paternally-expressed gene 1 protein; PEG1