The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.
D15S9; Probable E3 ubiquitin-protein ligase makorin-3; RING finger protein 63; RING-type E3 ubiquitin transferase makorin-3; RNF63; ZFP127; Zinc finger protein 127; ZNF127