MOBKL2A (Mps one binder kinase activator-like 2A), also known as MOB-LAK or MOB3A, is a 217 amino acid protein that regulates kinase activity. A member of the MOB1/phocein family, MOBKL2A is encoded by a gene that maps to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19.
MOB kinase activator 3A; MOB kinase activator 3B; MOB kinase activator-like 2B; MOB LAK; MOB-LAK; MOB1 (Mps One Binder) kinase activator-like 2B; Mob1 homolog 2A; Mob1 homolog 2b; MOB1, Mps One Binder kinase activator-like 2A; MOB1, Mps One Binder kinase activator-like 2B; MOB3A; MOB3B; MOBKL2A; MOBKL2B; monopolar spindle 1 binding, MOB1, domain containing; Mps one binder kinase activator-like 2A; Mps one binder kinase activator-like 2B