MOGT2 catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. It exhibits a preference toward monoacylglycerols containing unsaturated fatty acids in the order of C18:3 > C18:2 > C18:1 > C18:0. This protein plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. MOGT2 may play a role in diet-induced obesity.
2-acylglycerol O-acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DGAT2L5; Diacylglycerol acyltransferase 2-like protein 5; Diacylglycerol O-acyltransferase candidate 5; FLJ22644; hDC5; MGAT2; Monoacylglycerol O-acyltransferase 2