NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 [PubMed 9822604]).
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5'''-P1; diadenosine 5'; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1; Diphosphoinositol polyphosphate phosphohydrolase 1; DIPP; DIPP-1; DIPP1; Nucleoside diphosphate-linked moiety X motif 3; nudix (nucleoside diphosphate linked moiety X)-type motif 3; Nudix motif 3; P6-hexaphosphate hydrolase 1