The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly repeat-containing nucleoporin subset.
54 kDa nucleoporin; Nuclear pore complex protein Nup54; nucleoporin 54kD; nucleoporin 54kDa; Nucleoporin Nup54; Nucleoporin p54; NUP54