This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates. [provided by RefSeq, Jul 2008].
BHLHA1; Brain bHLH protein KW8; Class A basic helix-loop-helix protein 1; NDF2; NDRF; NeuroD-related factor; NeuroD2; neurogenic basic-helix-loop-helix protein; neurogenic differentiation 2; Neurogenic differentiation factor 2