This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013].
PCDH-Y; PCDH11; PCDH22; PCDHY; protocadherin 22; Protocadherin on the Y chromosome; Protocadherin prostate cancer; Protocadherin-11; Protocadherin-11 Y-linked; Protocadherin-22; Protocadherin-PC