This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
MGC2483; PEAMT; PEMPT; PEMT2; Phosphatidylethanolamine N-methyltransferase; phosphatidylethanolamine N-methyltransferase-like; phosphatidylethanolamine N-methyltransferase-like protein; Phospholipid methyltransferase; PLMT; PNMT