PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
InvitrogenPIM2 Antibody (5H66L51), ABfinity™ Rabbit Monoclonal PIM2 Antibody (5H66L51), ABfinity™ Rabbit Monoclonal
Cat # 702672
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