PIM3 is a memberof the Ser/Thr protein kinase family that may be involved in cell cycle progression and anti-apoptosis process. This protein has been implicated in proliferation of human hepatoma cell lines. PIM3 is widely expressed, with the exception of no expression observed in colon, thymus, and small intestine. PIM3 is expressed in human hepatoma cell lines but not in normal liver tissues.
KID-1/kinase induced by depolarization; pim-3 oncogene; PIM3; serine/threonine kinase Pim-3; Serine/threonine-protein kinase Pim-3